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1

Drug Design Targeting the Main Protease, the Achilles Heel of Coronaviruses

Yang, Haitao, Bartlam, Mark, Rao, Zihe

Journal:

Current Pharmaceutical Design

Year:

2006

Language:

english

File:

PDF, 597 KB

english, 2006

2

Production of Authentic SARS-CoV Mpro with Enhanced Activity: Application as a Novel Tag-cleavage Endopeptidase for Protein Overproduction

Xiaoyu Xue, Haitao Yang, Wei Shen, Qi Zhao, Jun Li, Kailin Yang, Cheng Chen, Yinghua Jin, Mark Bartlam, Zihe Rao

Journal:

Journal of Molecular Biology

Year:

2007

Language:

english

File:

PDF, 1.35 MB

english, 2007

3

Structures of Mycobacterium tuberculosis Penicillin-Binding Protein 3 in Complex with Five Î² -Lactam Antibiotics Reveal Mechanism of Inactivation

Lu, Zuokun, Wang, Han, Zhang, Aili, Liu, Xiang, Zhou, Weihong, Yang, Cheng, Guddat, Luke, Yang, Haitao, Schofield, Christopher J., Rao, Zihe

Journal:

Molecular Pharmacology

Year:

2020

File:

PDF, 1.12 MB

2020

4

Crystal structure of l -glutamate N -acetyltransferase ArgA from Mycobacterium tuberculosis

Yang, Xiuna, Wu, Lijie, Ran, Yajun, Xu, Ao, Zhang, Bing, Yang, Xiaolin, Zhang, Rongguang, Rao, Zihe, Li, Jun

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Year:

2017

Language:

english

File:

PDF, 1.73 MB

english, 2017

5

Crystal Structure of Mitochondrial Respiratory Membrane Protein Complex II

Fei Sun, Xia Huo, Yujia Zhai, Aojin Wang, Jianxing Xu, Dan Su, Mark Bartlam, Zihe Rao

Journal:

Year:

2005

Language:

english

File:

PDF, 3.21 MB

english, 2005

6

Structure, electronic properties and catalytic behaviour of an activity-enhancing CYP102A1 (P450BM3) variant

Whitehouse, Christopher J. C., Yang, Wen, Yorke, Jake A., Tufton, Henry G., Ogilvie, Lydia C. I., Bell, Stephen G., Zhou, Weihong, Bartlam, Mark, Rao, Zihe, Wong, Luet-Lok

Journal:

Dalton Transactions

Year:

2011

Language:

english

File:

PDF, 1.48 MB

english, 2011

7

Structure-function studies of the influenza virus RNA polymerase PA subunit

YingFang Liu, ZhiYong Lou, Mark Bartlam, ZiHe Rao

Journal:

SCIENCE CHINA Life Sciences

Year:

2009

Language:

english

File:

PDF, 742 KB

english, 2009

8

Design, Synthesis, and Evaluation of Novel Enterovirus 71 Inhibitors as Therapeutic Drug Leads for the Treatment of Human Hand, Foot and Mouth Disease (HFMD)

Zhang, Min, Wang, Ying, He, Wanli, Sun, Yao, Guo, Yan, Zhong, Weilong, Gao, Qiang, Liao, Mingyang, Wang, Xiangxi, Cai, Yan, Guo, Yu, Rao, Zihe

Journal:

Journal of Medicinal Chemistry

Year:

2020

Language:

english

File:

PDF, 3.19 MB

english, 2020

9

A Highly Active Single-Mutation Variant of P450BM3 (CYP102A1)

Christopher J. C. Whitehouse, Stephen G. Bell, Wen Yang, Jake A. Yorke, Christopher F. Blanford, Anthony J. F. Strong, Edward J. Morse, Mark Bartlam, Zihe Rao, Luet-Lok Wong

Journal:

Year:

2009

Language:

english

File:

PDF, 275 KB

english, 2009

10

Correction to the article “Crystal Structure of a Ferredoxin Reductase for the CYP199A2 System from Rhodopseudomonas palustris”

Feng Xu, Stephen G. Bell, Ying Peng, Eachan O.D. Johnson, Mark Bartlam, Zihe Rao, Luet-Lok Wong

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2010

Language:

english

File:

PDF, 33 KB

english, 2010

11

Crystal Structure of Human E1 Enzyme and its Complex with a Substrate Analog Reveals the Mechanism of its Phosphatase/Enolase Activity

Hui Wang, Hai Pang, Mark Bartlam, Zihe Rao

Journal:

Journal of Molecular Biology

Year:

2005

Language:

english

File:

PDF, 442 KB

english, 2005

12

Hepatitis A virus and the origins of picornaviruses

Wang, Xiangxi, Ren, Jingshan, Gao, Qiang, Hu, Zhongyu, Sun, Yao, Li, Xuemei, Rowlands, David J., Yin, Weidong, Wang, Junzhi, Stuart, David I., Rao, Zihe, Fry, Elizabeth E.

Journal:

Year:

2014

Language:

english

File:

PDF, 4.88 MB

english, 2014

13

Revealing various coupling of electron transfer and proton pumping in mitochondrial respiratory chain

Sun, Fei, Zhou, Qiangjun, Pang, Xiaoyun, Xu, Yingzhi, Rao, Zihe

Journal:

Current Opinion in Structural Biology

Year:

2013

Language:

english

File:

PDF, 2.79 MB

english, 2013

14

Cryo-EM structure of a herpesvirus capsid at 3.1 Å

Yuan, Shuai, Wang, Jialing, Zhu, Dongjie, Wang, Nan, Gao, Qiang, Chen, Wenyuan, Tang, Hao, Wang, Junzhi, Zhang, Xinzheng, Liu, Hongrong, Rao, Zihe, Wang, Xiangxi

Journal:

Year:

2018

Language:

english

File:

PDF, 10.89 MB

english, 2018

15

Hand-foot-and-mouth disease virus receptor KREMEN1 binds the canyon of Coxsackie Virus A10

Zhao, Yuguang, Zhou, Daming, Ni, Tao, Karia, Dimple, Kotecha, Abhay, Wang, Xiangxi, Rao, Zihe, Jones, E. Yvonne, Fry, Elizabeth E., Ren, Jingshan, Stuart, David I.

Journal:

Nature Communications

Year:

2020

Language:

english

File:

PDF, 3.15 MB

english, 2020

16

Adeno-associated virus 2 bound to its cellular receptor AAVR

Zhang, Ran, Cao, Lin, Cui, Mengtian, Sun, Zixian, Hu, Mingxu, Zhang, Rouxuan, Stuart, William, Zhao, Xiaochu, Yang, Zirui, Li, Xueming, Sun, Yuna, Li, Shentao, Ding, Wei, Lou, Zhiyong, Rao, Zihe

Journal:

Nature Microbiology

Year:

2019

Language:

english

File:

PDF, 2.25 MB

english, 2019

17

Three-step purification of gp96 from human liver tumor tissues suitable for isolation of gp96-bound peptides

Song-Dong Meng, Jian Song, Zihe Rao, Po Tien, George F. Gao

Journal:

Journal of Immunological Methods

Year:

2002

Language:

english

File:

PDF, 207 KB

english, 2002

18

Crystal structure of human transgelin

Ming Li, Shentao Li, Zhiyong Lou, Xiaoping Liao, Xiaodong Zhao, Zhaohui Meng, Mark Bartlam, Zihe Rao

Journal:

Journal of Structural Biology

Year:

2008

Language:

english

File:

PDF, 1003 KB

english, 2008

19

Crystal structure of a secreted lipase fromGibberella zeaereveals a novel “double-lock” mechanism

Zhiyong Lou, Ming Li, Yuna Sun, Ye Liu, Zheng Liu, Wenping Wu, Zihe Rao

Journal:

Year:

2010

Language:

english

File:

PDF, 1.02 MB

english, 2010

20

A structural view of the antibiotic degradation enzyme NDM-1 from a superbug

Yu Guo, Jing Wang, Guojun Niu, Wenqing Shui, Yuna Sun, Honggang Zhou, Yaozhou Zhang, Cheng Yang, Zhiyong Lou, Zihe Rao

Journal:

Year:

2011

Language:

english

File:

PDF, 747 KB

english, 2011

21

Opening Up the Group II Chaperonins

Journal:

Year:

2010

Language:

english

File:

PDF, 196 KB

english, 2010

22

The Crystal Structure of MCAT from Mycobacterium tuberculosis Reveals Three New Catalytic Models

Zexuan Li, Yishu Huang, Jing Ge, Hang Fan, Xiaohong Zhou, Shentao Li, Mark Bartlam, Honghai Wang, Zihe Rao

Journal:

Journal of Molecular Biology

Year:

2007

Language:

english

File:

PDF, 822 KB

english, 2007

23

The Catalytically Active Serine Protease Domain of Human Complement Factor I †

Tsiftsoglou, Stefanos A., Willis, Antony C., Li, Pengyun, Chen, Xuehui, Mitchell, Daniel A., Rao, Zihe, Sim, Robert B.

Journal:

Year:

2005

Language:

english

File:

PDF, 848 KB

english, 2005

24

Structural insights into the stabilization of active, tetrameric DszC by its C-terminus

Zhang, Liang, Duan, Xiaolu, Zhou, Daming, Dong, Zhe, Ji, Kaihua, Meng, Wuyi, Li, Guoqiang, Li, Xin, Yang, Haitao, Ma, Ting, Rao, Zihe

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2014

Language:

english

File:

PDF, 1.06 MB

english, 2014

25

Identification of serotonin 2A receptor as a novel HCV entry factor by a chemical biology strategy

Cao, Lin, Chen, Jizheng, Wang, Yaxin, Yang, Yuting, Qing, Jie, Rao, Zihe, Chen, Xinwen, Lou, Zhiyong

Journal:

Year:

2018

Language:

english

File:

PDF, 2.72 MB

english, 2018

26

Structural adaptations of norovirus GII.17/13/21 lineage through two distinct evolutionary paths

Qian, Ying, Song, Mohan, Jiang, Xi, Xia, Ming, Meller, Jarek, Tan, Ming, Chen, Yutao, Li, Xuemei, Rao, Zihe

Journal:

Journal of Virology

Year:

2018

Language:

english

File:

PDF, 2.94 MB

english, 2018

27

Unexpected mode of engagement between enterovirus 71 and its receptor SCARB2

Zhou, Daming, Zhao, Yuguang, Kotecha, Abhay, Fry, Elizabeth E., Kelly, James T., Wang, Xiangxi, Rao, Zihe, Rowlands, David J., Ren, Jingshan, Stuart, David I.

Journal:

Nature Microbiology

Year:

2018

Language:

english

File:

PDF, 2.57 MB

english, 2018

28

Structural basis for neutralization of hepatitis A virus informs a rational design of highly potent inhibitors

Cao, Lei, Liu, Pi, Yang, Pan, Gao, Qiang, Li, Hong, Sun, Yao, Zhu, Ling, Lin, Jianping, Su, Dan, Rao, Zihe, Wang, Xiangxi, Kwong, Peter D.

Journal:

Year:

2019

File:

PDF, 2.58 MB

2019

29

Crystal structure of a staphylokinase variant : A model for reduced antigenicity

Yuhang Chen, Gang Song, Fan Jiang, Liang Feng, Xiaoxuan Zhang, Yi Ding, Mark Bartlam, Ao Yang, Xiang Ma, Sheng Ye, Yiwei Liu, Hong Tang, Houyan Song, Zihe Rao

Journal:

Year:

2002

Language:

english

File:

PDF, 299 KB

english, 2002

30

Crystal structure of Bacillus thuringiensis Cry8Ea1: An insecticidal toxin toxic to underground pests, the larvae of Holotrichia parallela

Shuyuan Guo, Sheng Ye, Yanfeng Liu, Lei Wei, Jing Xue, Hongfu Wu, Fuping Song, Jie Zhang, Xiaoai Wu, Dafang Huang, Zihe Rao

Journal:

Journal of Structural Biology

Year:

2009

Language:

english

File:

PDF, 945 KB

english, 2009

31

Molecular coordination of αβ T-cell receptors and coreceptors CD8 and CD4 in their recognition of peptide-MHC ligands

George F. Gao, Zihe Rao, John I. Bell

Journal:

Trends in Immunology

Year:

2002

Language:

english

File:

PDF, 131 KB

english, 2002

32

Crystal structure and mutagenic analysis of GDOsp, a gentisate 1,2-dioxygenase from Silicibacter Pomeroyi

Jia Chen, Wei Li, Mingzhu Wang, Guangyu Zhu, Dongqi Liu, Fei Sun, Ning Hao, Xuemei Li, Zihe Rao, Xuejun C. Zhang

Journal:

Protein Science

Year:

2008

Language:

english

File:

PDF, 614 KB

english, 2008

33

Crystallization and preliminary X-ray crystallographic analysis of human geranylgeranyl pyrophosphate synthase

Yushu, Chen, Xiaofeng, Li, Zhiyong, Lou, Weina, Wang, Hai, Pang, Zihe, Rao

Journal:

Progress in Natural Science

Year:

2006

Language:

english

File:

PDF, 644 KB

english, 2006

34

Phylogeny reconstruction based on protein phylogenetic profiles of organisms*

Cheng, Miao, Ruan, Ge, Rao, Zihe

Journal:

Progress in Natural Science

Year:

2003

Language:

english

File:

PDF, 368 KB

english, 2003

35

Structure of the herpes simplex virus type 2 C-capsid with capsid-vertex-specific component

Wang, Jialing, Yuan, Shuai, Zhu, Dongjie, Tang, Hao, Wang, Nan, Chen, Wenyuan, Gao, Qiang, Li, Yuhua, Wang, Junzhi, Liu, Hongrong, Zhang, Xinzheng, Rao, Zihe, Wang, Xiangxi

Journal:

Nature Communications

Year:

2018

Language:

english

File:

PDF, 5.20 MB

english, 2018

36

Crystal structure of the hexamer of human heat shock factor binding protein 1

Xueqi Liu, Lingfeng Xu, Yiwei Liu, Xiaohang Tong, Guangyu Zhu, Xuejun C. Zhang, Xuemei Li, Zihe Rao

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2009

Language:

english

File:

PDF, 865 KB

english, 2009

37

Elucidation of strain-specific interaction of a GII-4 norovirus with HBGA receptors by site-directed mutagenesis study

Ming Tan, Ming Xia, Sheng Cao, Pengwei Huang, Tibor Farkas, Jarek Meller, Rashmi S. Hegde, Xuemei Li, Zihe Rao, Xi Jiang

Journal:

Year:

2008

Language:

english

File:

PDF, 1.92 MB

english, 2008

38

Crystal Structure of Human Pyrroline-5-carboxylate Reductase

Zhaohui Meng, Zhiyong Lou, Zhe Liu, Ming Li, Xiaodong Zhao, Mark Bartlam, Zihe Rao

Journal:

Journal of Molecular Biology

Year:

2006

Language:

english

File:

PDF, 1.44 MB

english, 2006

39

Seeing the change: TCR binds pMHC with an ‘induced-fit’

George F Gao, Zihe Rao

Journal:

Trends in Immunology

Year:

2002

Language:

english

File:

PDF, 16 KB

english, 2002

40

High-level expression and secondary structure analysis of the bovine mature prion protein

Dawei Wang, Huaiyi Yang, Zihe Rao, Bo Tian

Journal:

Chinese Science Bulletin

Year:

2000

Language:

english

File:

PDF, 432 KB

english, 2000

41

Preparation of the selenomethionine derivative of tabtoxin resistance protein

Hongzhen He, Yu Shao, Chen Yuhang, Liu Bingbing, Cao Zhenbo, Jiang Fan, Liu Yiwei, Tang Hong, Liu Jinyuan, Zhao Nanming, Rao Zihe

Journal:

Chinese Science Bulletin

Year:

2001

Language:

english

File:

PDF, 488 KB

english, 2001

42

Crystal structures of Nipah and Hendra virus fusion core proteins

Zhiyong Lou, Yanhui Xu, Kehui Xiang, Nan Su, Lan Qin, Xu Li, George F. Gao, Mark Bartlam, Zihe Rao

Journal:

Year:

2006

Language:

english

File:

PDF, 1.08 MB

english, 2006

43

Crystal structure of human coactosin-like protein at 1.9 Å resolution

Xuemei Li, Xueqi Liu, Zhiyong Lou, Xin Duan, Hao Wu, Yiwei Liu, Zihe Rao

Journal:

Protein Science

Year:

2004

Language:

english

File:

PDF, 294 KB

english, 2004

44

Expression, Purification, Crystallization and Preliminary X-Ray Analysis of Human Spindlin1, an Ovarian Cancer-Related Protein

Jiang, Fuguo, Zhao, Qiang, Qin, Lipeng, Pang, Hai, Pei, Xuetao, Rao, Zihe

Journal:

Protein & Peptide Letters

Year:

2006

Language:

english

File:

PDF, 57 KB

english, 2006

45

Adeno-associated virus 2 bound to its cellular receptor AAVR

Zhang, Ran, Cao, Lin, Cui, Mengtian, Sun, Zixian, Hu, Mingxu, Zhang, Rouxuan, Stuart, William, Zhao, Xiaochu, Yang, Zirui, Li, Xueming, Sun, Yuna, Li, Shentao, Ding, Wei, Lou, Zhiyong, Rao, Zihe

Journal:

Nature Microbiology

Year:

2019

File:

PDF, 2.25 MB

2019

46

Protein recognition in ferredoxin–P450 electron transfer in the class I CYP199A2 system fromRhodopseudomonas palustris

Stephen G. Bell, Feng Xu, Eachan O. D. Johnson, Ian M. Forward, Mark Bartlam, Zihe Rao, Luet-Lok Wong

Journal:

JBIC Journal of Biological Inorganic Chemistry

Year:

2010

Language:

english

File:

PDF, 809 KB

english, 2010

47

Cytochrome P450 enzymes from the metabolically diverse bacterium Rhodopseudomonas palustris

Stephen G. Bell, Nicola Hoskins, Feng Xu, Domenico Caprotti, Zihe Rao, Luet-Lok Wong

Journal:

Biochemical and Biophysical Research Communications

Year:

2006

Language:

english

File:

PDF, 212 KB

english, 2006

48

Structural characterization of Mumps virus fusion protein core

Yueyong Liu, Yanhui Xu, Zhiyong Lou, Jieqing Zhu, Xuebo Hu, George F. Gao, Bingsheng Qiu, Zihe Rao, Po Tien

Journal:

Biochemical and Biophysical Research Communications

Year:

2006

Language:

english

File:

PDF, 797 KB

english, 2006

49

Basis for fusion inhibition by peptides: analysis of the heptad repeat regions of the fusion proteins from Nipah and Hendra viruses, newly emergent zoonotic paramyxoviruses

Yanhui Xu, Shan Gao, David K. Cole, Junjie Zhu, Nan Su, Hui Wang, George F. Gao, Zihe Rao

Journal:

Biochemical and Biophysical Research Communications

Year:

2004

Language:

english

File:

PDF, 1.02 MB

english, 2004

50

Following the rule: formation of the 6-helix bundle of the fusion core from severe acute respiratory syndrome coronavirus spike protein and identification of potent peptide inhibitors

Jieqing Zhu, Gengfu Xiao, Yanhui Xu, Fang Yuan, Congyi Zheng, Yueyong Liu, Huimin Yan, David K Cole, John I Bell, Zihe Rao, Po Tien, George F Gao

Journal:

Biochemical and Biophysical Research Communications

Year:

2004

Language:

english

File:

PDF, 259 KB

english, 2004

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